Abstract
Objectives: Foreign body reaction to absorbable hemostatic agents may mimick recurrent brain tumor or abscess on postoperative MRI. Their appearance on intraoperative MRI and their use as resection borders marker have been not previously described. This study evaluates the intraoperative MRI appearance of absorbable oxidized regenerated cellulose in surgery of cerebralgliomas. Methods: 72 patients with cerebral gliomas were intraoperatively examined with high field MRI (1.5 T). 32 patients presented low-grade and 40 high-grade gliomas. After tumor resection the tumor bed was covered with absorbable oxidized regenerated cellulose. Results: The absorbable hemostat presented a hyperintense signal on MRI-T1 sequences in all patients. Tumor remnants under the hemostatic agent could be identified. Conclusions: Oxidized Regenerated Cellulose can be easily observed as a hyperintense signal lining covering the borders of the surgical cavity on intraoperative MRI-T1 sequences. It may be a useful marker of tumor resection borders of cerebral gliomas.
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