Abstract
Histopathological examination is still the gold standard for diagnoses of oral-maxillofacial lesions, but it is invasive and time-consuming. Optical coherence tomography (OCT) provides a kind of noninvasive, label-free, real-time and high-resolution imaging technology. In this study, in order to assess the feasibility of OCT in oral clinical application, fresh excised tissue specimens from 59 patients undergoing oral-maxillofacial surgery were imaged in detail by using a benchtop swept-source OCT system. It is shown that different lesions or tissues can be obviously distinguished based on their different microstructural features in OCT images, and the features are similar to those of their corresponding histopathological images. It is proven that OCT has great feasibility and potential as a diagnostic aid for surgeons in oral medicine.
Highlights
Oral cancer ranks eighth among the most common cancers in the world, and theve-year survival rate of patients is still less than 60%.1 Surgery is one of the most common and e®ective methods to treat oral cancer
Visual examination is the most commonly used method for diagnosing oral and oral-maxillofacial lesions, but the accuracy is highly dependent on the experience of the surgeons
On the right-hand side of the black dotted curve is the area destroyed by cancerous tissues, and the region is not invaded on the left-hand side
Summary
Oral cancer ranks eighth among the most common cancers in the world, and theve-year survival rate of patients is still less than 60%.1 Surgery is one of the most common and e®ective methods to treat oral cancer. Resolutions of ultrasound imaging, X-ray computed tomography and magnetic resonance imaging are not enough to accurately identify oral lesions in most cases The characteristics such as high resolution and noninvasiveness make optical imaging techniques have a great potential in biomedicine. To the best of our knowledge, this is therst study discussing the OCT intraoperative imaging of various types of oral-maxillofacial lesions in detail
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
