Abstract
A prototype intraoperative hand-held optical coherence tomography (OCT) imaging probe was developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic probe was designed based on electrostatically driven optical fibers, and packaged into a catheter probe in the form factor of clinically accepted Bayonet shaped neurosurgical probes. Optical properties of the probe were measured to have a ~20 μm spot size, 5 mm working distance and 4 mm field of view. Feasibility of this probe for structural and Doppler shift imaging was tested on porcine femoral blood vessel imaging.
Highlights
Pituitary adenomas account for 10%–15% of all diagnosed intracranial tumors and the diagnosed cases are suggested to be increasing with the use of modern imaging techniques [1]
A prototype intraoperative hand-held optical coherence tomography (OCT) imaging probe was developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic probe was designed based on electrostatically driven optical fibers, and packaged into a catheter probe in the form factor of clinically accepted Bayonet shaped neurosurgical probes
Optical properties of the probe were measured to have a ~20 μm spot size, 5 mm working distance and 4 mm field of view. Feasibility of this probe for structural and Doppler shift imaging was tested on porcine femoral blood vessel imaging
Summary
Pituitary adenomas account for 10%–15% of all diagnosed intracranial tumors and the diagnosed cases are suggested to be increasing with the use of modern imaging techniques [1]. Subarachnoid hemorrhage (SAH) caused by a cerebral aneurysm that ruptures occurs in about 40–50 per 100,000 people over age 30 [3] Both pituitary tumor and aneurysm can be operated on using modern microsurgical techniques through open craniotomy and minimally invasive surgeries. Various probes have been developed to perform OCT imaging where the scanning mechanisms have been based on piezoelectric cantilever scanning through a GRIN lens [15,16], electroactive polymer cantilever [17] and scanning mirrors [18,19] These designs may be optimal for applications such as mouth and skin imaging, and open knee surgery guidance. With the handheld bayonet form factor, OCT can be used to image internal tissue microstructures that was previously unavailable to surgeons, it may become a powerful imaging technology for surgery guidance
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