Abstract
Intraoperative blood salvage reduces the requirements for allogenic blood transfusion and transfusion related inflammatory response in abdominal aortic aneurysm surgery: Blood transfusion and abdominal aortic aneurysm surgery
Highlights
Intraoperative blood salvage (IBS) is a procedure involving recovering blood looses during surgery and reinfusing it into the patient with a purpose to reduce the perioperative morbidity and mortality associated with complications after administration of allogenic transfusion (AT)
The aim of this study was to investigate whether the IBS reduces the need for allogenic transfusion requirements and for non-invasive ventilation (NIV) and/or oxygen supplementation and whether it was associated with decreased levels of inflammatory markers following abdominal aortic aneurysm (AAA) surgery
The postoperatively average white blood cell count (WBCC) was significantly higher among patients in NCS group compared to those from CS group (12.89 x 109 vs. 10.44 x109; p=0.014)
Summary
Uvod: Intraoperativno spašavanje krvi je procedura koja zahteva upotrebu posebnih aparata za prikupljanje i obradu izgubljene krvi tokom hirurških intervencija i vraćanja iste nazad u cirkulacioni sistem bolesnika, a sa ciljem redukcije postoperativnog morbiditeta i mortaliteta, povezanih sa komplikacijama nakon primene alogenih transfuzija. Cilj ove studije bio je ispitivanje efikasnosti intraoperativnog spašavanja krvi kroz smanjenje potrebe za alogenim transfuzijama, učestalosti upotrebe neinvazivne (NIV) ventilacije i/ili kiseonične suplementacije i nivoa vrednosti markera zapaljenja nakon operacija aneurizme abdominalne aorte. Perioperativno spašavanje krvi pomoću „Haemonetics cell saver 5+” korišćeno je kod 24/51 (47,05 %) pacijenata (CS grupa), dok 27/51 (52,95%) nije dobijalo autotransfuziju (NCS grupa). Praćene su vrednosti markera zapaljenja (broj leukocita, C-reaktivni protein (CRP), prokalcitonin (PCT) i fibrinogen), potreba za neinvazivnom ventilacijom (NIV) i kiseoničnom suplementacijom, kao i količina upotrebljene alogene transfuzije. Rezultati: Rezultati pokazuju da je potreba za intra i postoperativnim alogenim transfuzijama krvi bila značajno veća kod bolesnika iz NCS grupe u poređenju sa onima iz CS grupe (3,63 ± 1,07 naspram 0,58 ± 0,83 jedinica po pacijentu; p < 0,001). Neinvazivna respiratorna potpora je češće korišćena u NCS grupi (4/27) u poređenju sa CS grupom (1/24), ali ova razlika nije bila
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