Abstract

Reliable measures of optic nerve status are important parameters for epidemiologic and clinical studies of glaucoma. Stereo fundus photography has been used to reduce Interobserver variation, but little data have been reported quantifying the level of agreement in these situations. This article examines chance-corrected Intraobserver and Interobserver agreement for horizontal and vertical cup:disc ratios and width of the narrowest remaining neuroretinal rim on stereo, color, fundus photographs. Intraobserver agreement was substantial to almost perfect for both readers (kappas between 0.82 and 0.86 for horizontal and vertical cup:disc ratios and 0.71 for the neuroretinal rim). Interobserver agreement was also substantial (kappas of 0.71 for horizontal cup:disc ratio, 0.74 for vertical cup:disc ratio, and 0.58 for the neuroretinal rim). Both Intraobserver and Interobserver agreement were best for glaucoma patients followed by ocular hypertensives and controls. Dichotimizing cup:disc ratios into suspicious or not suspicious using a range of cutoff points (≥0.5, ≥0.6, and ≥0.7 disc diameters [DD]) had little effect on agreement levels. Estimation of the status of the optic nerve is complex, requiring judgment about the shape and structure of the cup. Agreement is optimized by using stereo photographs, using the same observer and, when evaluating progression, comparing photographs from different points in time at a single sitting.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.