Intranodal palisaded myofibroblastoma originating from retroperitoneum: an unusual origin

Jayesh Sagar,Hemachandran Manikkapurath,Athanasia Vargiamidou

doi:10.1186/1472-6890-11-7

Jayesh Sagar, Hemachandran Manikkapurath + Show 1 more

Open Access

https://doi.org/10.1186/1472-6890-11-7

Copy DOI

Abstract

BackgroundIntranodal palisaded myofibroblastoma is one of the primary mesenchymal tumours. The inguinal region is the commonest site of this rare tumour. As there are only about 55 such cases reported in the literature, the precise aetiology and pathogenesis have yet to be explained adequately. Here we report a case of a 72 year old man presented with incidental finding of intranodal palisaded myofibroblastoma in the retroperitoneal region.Case PresentationA 72-year old man presented with abdominal pain in right upper quadrant with an incidental finding of abdominal mass in the right flank. The computerised tomogram scan of abdomen confirmed acute cholecystitis with a 5 x 5 cm retroperitoneal mass. He underwent cholecystectomy with excision of this mass. He recovered well following his operation and was discharged from the hospital. Histological examination confirmed the diagnosis of intranodal palisaded myofibroblastoma.ConclusionTo our knowledge, this is the first case of intranodal palisaded myofibroblastoma originating from retroperitoneum. Along with the rarity of this case, we also discussed its typical histopathological findings, aetiology and pathogenesis.

Highlights

Intranodal palisaded myofibroblastoma is one of the primary mesenchymal tumours
In this case report we presented another case of Intranodal palisaded myofibroblastoma (IPM), but originating from retroperitoneum
Among primary mesenchymal tumours, intranodal palisaded myofibroblastoma is very rare. It was initially described by Deligdish and Katz as neurilemmoma or schwanoma and later classified as palisaded myofibroblastoma by Weiss [7,8]

Summary

Background

In comparison to secondary mesenchymal tumours, primary mesenchymal tumours involving lymph nodes are very rare. Intranodal palisaded myofibroblastoma (IPM), one of the rare primary mesenchymal tumours, was first described in English literature in 1968, though not classified as Intranodal palisaded myofibroblastoma [2]. These tumours arise from the lymph nodes and are almost always seen in the inguinal lymph nodes, few cases of mediastinal and submandibular lymph node origins have been reported [3]. English literature [4,5,6] In this case report we presented another case of IPM, but originating from retroperitoneum. Amianthoid fibres were identified though in few areas of the tumour (figure 4)

Conclusions

Katz DR

14. Abd el-All HS