Intramucosal adenocarcinoma arising from ectopic gastric mucosa in the upper esophagus treated successfully with endoscopic mucosal resection.

Abstract

Heterotopic gastric mucosa (HGM), also referred to as “inlet patch”, is an ectopic salmon-colored gastric mucosa that is located just distal to the upper esophageal sphincter [1]. Most HGM are asymptomatic and detected incidentally during endoscopy. In endoscopic studies, the reported incidence varies from 0.29 to 13.8 % [2, 3] but autopsy studies have reported incidence ranges between 12 and 20 % [4, 5]. Although most consider HGM as clinically negligible entity, it has been associated with symptoms such as globus, dysphagia, and pain and has been linked to acid-related complications such as bleeding, ulceration, stricture, and fistula. Moreover, in exceedingly rare cases, dysplastic changes and malignancies in association with HGM have also been reported, [1]. We here report a case of intramucosal adenocarcinoma arising in HGM of the cervical esophagus, successfully treated with endoscopic mucosal resection (EMR). Case Report