Abstract
The neighbouring pyrimidine group of the conjugate acid of 2-(4-aminopyrimidin-2-ylthio)-2-methyl-p-nitropropananilide (3) is an effective nucleophilic catalyst for the hydrolysis of the p-nitroanilide function. The reactivity of pyrimidine nitrogen parallels that of the carboxy group, and the mechanisms of the reactions with neighbouring amide functions are similar in detail.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
