Abstract
The course of the reactions that occur when stereochemically rigid trans-perhydronaphthalene1,4-diol monosulfonate esters (1-0) are treated with alkali metal tert-amylate in refluxing benzene depends on the relative orientation of the leaving group and the tertiary hydroxyl group. An equatorial sulfonate ester group favors homofragmentation leading to the cyclopropane derivative 15. In case of an axial sulfonate ester group β-elimination, which strongly depends on the stereochemistry of the tertiary deprotonated hydroxyl group, is the main reaction path
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
