Abstract
Postoperative morbidity after esophagectomy and gastric tube formation depends on the vascularization of the gastric conduit. The aim of this experimental study was to assess a recently developed microprobe (O2C®, Fa. LEA Medizintechnik) monitoring the gastric microcirculation from the endoluminal side. Eighteen patients with no evidence of gastric pathology were included in this study. During conventional gastroscopy the microprobe was introduced via the working channel and positioned in well defined areas of the antrum, corpus and fundus. The microprobe measured the gastric blood flow (BF, in perfusion units, PU) and oxygen saturation (SO2, in %) by a combined Laser-Doppler and Tissue Spectrometer. Mucosal blood flow of the fundus was significantly higher compared to the corpus (Corpus: 193 PU ± 47 SD, Fundus: 225 PU ± 41 SD; p = 0,012) whereas no significant different blood flow between antrum and fundus could be demonstrated (Antrum: 201 PU ± 40 SD, Fundus: 223 PU ± 29). Mucosal oxygen saturation of the antrum was significantly higher compared to the fundus (Antrum: 82 % ± 10 SD, Fundus: 73 % ± 10 %; p = 0,0007).
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