Intralesional Zinc Sulfate 2% Vs Intralesional Vitamin D In The Treatment Of Planter Warts

Abstract

Abstract Background verrucae are benign proliferations seen in skin and mucosae due to infection with papillomaviruses. Aim and Objectives the aim of this work is to compare the clinical efficacy of intra-lesional 2% zinc sulfate solution vs intralesional vitamin D in the treatment of planter warts, Subjects and Methods this is Three armed single blinded randomized clinical trial included 105 patients presented with planter warts, Patients were all recruited from the Dermatology outpatient clinic at Ain-Shams University Hospital and Almateria hospital during the period From July 2018 to July 2019, Patients included in the present study were divided into 3 groups, 35 patients per group by simple randomization process which could allocate patients to either of three arms randomly and each patient would have an equal chance to be allocated to either of the three arms, Results There was no statistically significant difference between the 3 studied groups as regard the response to treatment after 1st, 2nd and 4th session. While after the 3rd session, there was statistically significant increase in the numbers of partial responders in the 3 studied groups (P = 0.023), Conclusion the current study showed that intralesional injection of 2% zinc sulfate is a better therapeutic option in the treatment of planter warts in comparison with intralesional vit D,