Abstract

Intralesional injection of Candida antigen appears to be an effective alternative for the treatment of warts. To determine the efficacy and safety of this treatment. We retrospectively reviewed records of all children who received intralesional injection of Candida antigen at our center from January 2008 to July 2013. From a total of 220 patients, 156 (70.9%) had a complete response, 37 (16.8%) had a partial response, and 27 (12.2%) had no improvement. An average of 2.73 treatments was needed. Forty-seven of the patients with more than one wart (21.3%) also noted at least partial resolution of untreated warts at distant sites. Twenty-seven of the 47 patients (57.4%) had complete resolution. All treated patients experienced some discomfort at the time of the injection, but no serious side effects were reported. We report our results using this approach in a large group of children. Intralesional injection of Candida antigen is an effective and safe therapy for children with multiple and recalcitrant cutaneous warts.

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