Intrafamilial transmission and clustering of COVID-19: a socioepidemiological perspective.

Abstract

The dynamics of COVID-19 transmission occurring in familial clusters may be related to sociodemographic and epidemiological characteristics of cases and contacts. The aim of this study was to identify the dynamics of COVID-19 transmission in families with more than one documented case. Data of about 58 familiar clusters of COVID-19 was gathered and followed up clinically and by telephonic interview. Age, gender, social security plan, comorbidities, occupation, incubation, and symptoms were analyzed using Students' t-test and Chi squared test. The contacts were younger and healthier than cases, and students were predominant (28%). Among the symptomatic contacts, reverse transcription polymerase chain reaction yielded a positive rate of 69%. There were 2.93 contacts per case. Families with clustered cases had more family members when compared to families without clustered cases (4.2 vs. 3.3; p = 0.022). Mean age of contacts in families with clustered cases compared to families without clustered cases also showed differences (29.5 vs. 35.7; p = 0.047). Characterization of cases and contacts amidst a pandemic is essential for the effective implementation of health policies and research perspectives.