Abstract

Intraductal papillary mucinous neoplasms of the pancreas (IPMNs) are precancerous lesions. Anatomically, IPMNs are classified as main duct-type and branch duct-type. Histologically, these neoplasms are grouped into 4 categories: intestinal, pancreatobiliary, oncocytic, and gastric. Patients diagnosed with IPMN have been shown to have an increased risk of malignancy of the pancreatic tumor, but also an increased risk of associating cancers with extrapancreatic localization. Among the factors associated with the risk of malignancy of IPMNs are the involvement of the main pancreatic duct or branch duct, tumor size, diameter of the main pancreatic duct, and histological type. Regarding IPMN-associated extrapancreatic cancers, gastric adenocarcinoma and colorectal adenocarcinoma were the most reported.

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