Intradermal use of convalescent serum against measles: Preliminary report

Abstract

Summary 1. Forty persons, two adults and thirty-eight children, have been given recent convalescent measles serum intradermally. 2. The serum was given in 0.4 c.c. amounts intradermally on successive days until 2 c.c. were given. 3. Thirty-four children and two adults did not develop measles. Two children developed uncomplicated measles before the course was completed. Two children developed attenuated measles fourteen days after the inoculations. 4. It is believed at the present time that recent convalescent measles serum has enough measles antigen available to produce an active immunity when this serum is given intradermally in at least the amounts suggested. 5. The intradermal employment of recent convalescent measles serum in the amounts suggested provides an economical use of this product.