Abstract
To achieve fertilization and cleavage by spermatozoa retrieved by testicular biopsy from a male with testicular tubular atrophy. Clinical trial. Private reproductive institute. Azoospermic male with demonstrated testicular tubular atrophy and almost complete spermatogenic arrest. Open biopsy retrieval of testicular tissue and sperm followed by intracytoplasmic sperm injection. Fertilization and cleavage. One four- to six-cell embryo was formed after intracytoplasmic sperm injection of five eggs with extruded polar bodies by retrieved sperm. Intracytoplasmic sperm injection after testicular sperm aspiration may be attempted in cases with severely decreased spermatogenesis and result in fertilization, cleavage, and embryo transfer.
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