Abstract

SYMPTOMATIC intracranial tuberculoma is a rare CNS manifestation of<i>Mycobacterium tuberculosis</i>infection in the United States but is common in India, Africa, and South America. We describe a patient with a four-year history of uncinate seizures and violent behavior who had a temporal lobe tuberculoma. <h3>Report of a Case</h3> An emaciated, 41-year-old man complained of persistent hiccoughs, vomiting, and headache. Four years earlier, he began to experience a sense of depersonalization, coexistent with the perception of a putrid odor. Thereafter, he was unable to recall his actions. During one of these periods, he killed his wife. During his three-year incarceration, he had more frequent olfactory hallucinations that could then also be associated with dyspepsia, hiccoughs, nausea, and headache. Major motor seizures did not occur. A physical examination disclosed draining axillary adenopathy. A biopsy specimen demonstrated a granulomatous process with multinucleated giant cells and central necrosis. Neither acid-fast bacilli nor fungi

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