Abstract
It has been specifically stated by various authorities that there is an increase in the intracranial pressure at high altitudes. In view of this assumption, it was proposed to study the effects of altitude on the intracranial pressure in a patient with a large cranial defect. The subject owes his life to the fact that, with dura torn and cerebral substance protruding from the wound, he was fortunate enough to be transported by air to a hospital for specialized neurosurgical treatment. The tremendous size of the cranial defect which resulted and the fact that there was no retraction of the scar made direct and unusual instrumental observations possible. There are conflicting reports in the literature concerning the behavior of intracranial pressure at high altitudes when the subject is breathing oxygen and when he is anoxic. Walsh1described the case of a patient with a cranial defect following craniotomy in
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