Intracranial Immature teratoma diagnosed in a fetus- case report

Abstract

This 39 year-old female received prenatal care at local clinics. Her prenatal exam was in normal limit. Unfortunately, an enlarged brain tumor of the fetus was noted at 29 weeks of gestational age. She was transferred to our hospital for further evaluation. Then magnetic resonance imaging study(MRI) of the fetus was performed, the result showed huge multicystic lesions in brain with obliteration of cerebral, cerebellar parenchyma and ventricles, poor differentiation of intracranial structure, poor development of upper spinal cord, and craniomegaly. We also discussed this case with the pediatrician and neurology surgeon. Poor prognosis of the baby was impressed. Then we informed the survey result and the prognosis to the patient and her husband. The decided to terminate the pregnancy. We arranged schedued cesarean section for her because of larged biparietal diameter. The baby was delivered at the gestation age of 32 2/7 weeks, with body weight 4280 gram, the Apgar scores were 3 and 2 at 1 and 5 minutes after delivery, respectively. The baby was expired later. We arranged the autopsy, the result revealed the brain is asymmetrical and almost totally replaced by the large solid and multicystic tumor measuring 17.5 × 13.5 × 4.5 cm and weighing 800.0 gm as a whole. The tumor is yellowish white and soft to firm with areas of calcification and jelly-like content. The pathologic result was immature teratoma.