Abstract
Germ cell tumours represent about 3 to 8% of pediatric brain tumours. Occurrence of diabetes insipidus is common in the case of suprasellar germ cell tumors. The diagnosis may be advanced by MRI owing to the location and relatively univocal characteristics of the lesion signal. The existence of a bifocal mass developed in both suprasellar region and pineal zone is highly suggestive of a germinoma. The most important notion is to recognize that at the time of diabetes insipidus diagnosis in a child, the cerebral mass might be too small to be identified by MRI. In such patients, repeating imaging study should be obtained.
Highlights
Germ cell tumours represent about 3 to 8% of pediatric brain tumours
A 12-year-old-girl was admitted at the emergency department because of areactive mydriasis associated with oculomotor paresis of the left eye. She was explored by brain MR for hypotrophy and occurrence of diabetes insipidus
A suprasellar mass was evidenced and a biopsy was undertaken which led to the diagnosis of lymphocytic hypophysitis (Fig. 1)
Summary
Germ cell tumours represent about 3 to 8% of pediatric brain tumours. Occurrence of diabetes insipidus is common in the case of suprasellar germ cell tumors. The diagnosis may be advanced by MRI owing to the location and relatively univocal characteristics of the lesion signal. The existence of a bifocal mass developed in both suprasellar region and pineal zone is highly suggestive of a germinoma. The most important notion is to recognize that at the time of diabetes insipidus diagnosis in a child, the cerebral mass might be too small to be identified by MRI. In such patients, repeating imaging study should be obtained. Key-word: Brain neoplasms, in infants and children
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