Abstract
Systemic lupus erythematosus (SLE) is a chronic disease with multiple pathologies that can affect every organ system of the body including central nervous system. Intracerebral aneurysms and subarachnoid hemorrhage (SAH) are one of comparatively rarer manifestations of central nervous system SLE. Here we present a case of known SLE complicated by the rupture of intra cerebral aneurysm at basilar artery tip which was successfully treated with endovascular coiling.
Highlights
Systemic lupus erythematosus (SLE) is a chronic and systemic disease that affects every organ including CNS
Underlying vasculopathic changes of small arterioles and veins in SLE can lead to spontaneous IC hemorrhage, without aneurysm or any other causative factor, as has been reported earlier.[4]
SLE is more commonly associated with multiple IC aneurysms and the patients are usually younger
Summary
Systemic lupus erythematosus (SLE) is a chronic and systemic disease that affects every organ including CNS. CNS is involved in approximately 40% of all SLE patients with wide range of neuro-psychiatric symptoms.[1,2] The main underlying pathology of intracranial (IC) aneurysm and its rupture is lupus vasculitis and fragility of blood vessels due to prolonged use of steroid. Shrestha et al Intracranial Aneurysm with Systemic Lupus Erythematosus Treated by Endovascular Intervention
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