Abstract
Leadbetter and Burkland (1938) were the first to describe fibro-muscular hyperplasia as a cause of renal artery stenosis and consequent renovascular hypertension. It is now well established that fibromuscular hyperplasia also occurs in other arteries, such as the coeliac, iliac, splenic and mesenteric arteries (Palubinskas, Perloff and Newton, 1966; Wylie, Binkley and Palubinskas, 1966; Lian and Eyler, 1967). Recently, fibro-muscular hyperplasia has been reported to involve the internal carotid artery (Ehrenfeld, Stoney and Wylie, 1967; Morris, Lechter and DeBakey, 1968). Huber and Fuchs (1967) observed a beaded appearance of the intracranial arteries on carotid angiograms in two girls aged two and seven, and supposed it to be due to fibro-muscular hyperplasia. To our knowledge, however, an histologically verified case of fibro-muscular hyperplasia of the intracranial arteries has not been described. We were recently confronted with a case of anterior cerebral aneurysm associated with fibro-muscular hyperplasia of the renal and internal carotid arteries.
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