Intracerebral haemorrhage growth is influenced by anticoagulation intensity

Weimin Yang,Hui Li,Nick Paltoglou,Yiting Mao,Churilov Leonid,Bernard Yan

doi:10.15761/ndt.1000107

Abstract

Intracerebral haemorrhage growth is influenced by anticoagulation intensity

Highlights

Intracerebral hemorrhage (ICH) is a stroke subtype accounting for approximately 10% – 15% of all strokes [1] and has an annual incidence of approximately 25 per 100,000 [2]
We aimed to investigate the effects of anticoagulation intensity on hematoma expansion
From January 1, 2008 to August 1, 2014, we identified 583 ICH patients in Royal Melbourne Hospital, 279 patients excluded by reason of the lack of a second CT scan (CT 2), 22 patients excluded because of surgical hematoma evacuation, 4 patients intraventricular hemorrhage, 10 patients without clinical data were excluded

Summary

Introduction

Intracerebral hemorrhage (ICH) is a stroke subtype accounting for approximately 10% – 15% of all strokes [1] and has an annual incidence of approximately 25 per 100,000 [2]. The one month case fatality rate is approximately 40% and rising to 55% in 1 year [2]. The 10-year survival rate is approximately 20% to 25% [3]. The rate of functional independence after ICH at 1 year varies between 12% to 39% [2,4]. Various factors have been shown to influence outcome in ICH, including age, initial hematoma volume, hematoma expansion (HE), neurologic deficit, intraventricular extension, and infratentorial location [5]. Approximately 10 mL increase in hematoma volume over 24 hours was strongly associated with poor outcome [5]. We aimed to investigate the effects of international normalized ratio (INR) on hematoma expansion post ICH

Objectives

Methods

Results

Conclusion