Intracerebral Haemorrhage Caused by Endosulfan Intoxication: A Case Report

Abstract

Introduction: many chemical substances used in industry, households, agriculture, often result in bad side effects to people and environment. As an agricultural country, the frequency of the use of pesticides in Indonesia is quite high since those chemical substances are still badly needed by the people for their farming. The bad side effects should strongly be avoided. Related with the disadvantages or dangers of those, especially pesticides. It is often found that a sudden death can be related with intoxication. It is sometimes difficult to differentiate them, whether if caused by disease, violence or intoxication. During 2008-2018 extra toxicological examination performed in the Forensic Laboratory of Toxicology in East Java Regional Police Headquarter in the period of 2008 up to 2018 indicated 44% of 25 cases were dominated by intoxication, which were mostly caused by propoxur intoxication (carbamate insecticide) 90 % and by endosulfan 10%. It means that endosulfan as the restricted pesticides can be the cause of death, wether by accidental action or even homicide and suicide action. Objective: To be able to analyze the changes or the clinical effects due to endosulfan intoxication, especially in death acutely which shown the intracerebral haemorrage from the death. Method: case report of the sudden death on women suspected poisoning by endosulfan. Conclussion: Symptoms of acute endosulfan poisoning include hyperactivity, tremors, convulsion, lack of coordination, staggering, difficulty of breathing, nausea/vomiting, diarrhea, and in severe cases, unconsciousness and many cases of sub lethal poisoning have resulted in permanent brain damage.