Abstract
Intracellular recordings were made from 302 canine intracardiac ganglion cells with intact synaptic connections. Fifty-two % of these cells exhibited spontaneous membrane potential changes consisting primarily of miniature excitatory postsynaptic potential (EPSP)-like depolarizations upon which an action potential or burst of action potentials was sometimes evoked. Most of the spontaneous potential changes are presumed to be synaptically mediated involving nicotinic mechanisms because they were blocked by low Ca 2+ high Mg 2+ and hexamethonium solutions.
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