Abstract
The concentration of free Ca 2+ in the cell cytoplasm is likely to be the most important parameter which should be considered in assessing the contribution of Ca 2+ to regulation of neurotransmitter release, memory development and cell growth. Quantitative measurement of the free Ca 2+ concentration and elucidation of the membrane transduction systems which control this parameter in aged neuronal cells may make a significant contribution to further define the role of Ca 2+ in the ageing nervous system.
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