Abstract
Cellular oscillations of cytosolic free Ca 2+ ([Ca 2+] i) have been observed in many cell types in response to cell surface receptor agonists acting through inositol 1,4,5-trisphosphate (InsP 3). In a number of cases where appropriate spatial and temporal resolution have been used to examine these [Ca 2+] i oscillations, they have been found to be organized as repetitive waves of Ca 2+ increase that propagate through the cytosol of individual cells. In some cases Ca 2+ waves also occur as a single pass through stimulated cells. This review discusses the factors underlying the spatial organization of [Ca 2+] i signals in the form of Ca 2+ waves. In addition, potential mechanisms for the initiation and subsequent propagation of these Ca 2+ waves are described.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
