Abstract
The process of biosynthesis of silver nanoparticles is a simple, cost effective and eco-friendly approach. Biosynthesis of silver nanoparticles using some commonly available edible mushroom extracts and their antimicrobial activity was demonstrated in the current study. The formation of silver nanoparticles was confirmed by UV, FTIR and SEM and antibacterial activity was tested using disc diffusion method. From the results it is confirmed the successful formation of silver nanoparticles using mushroom extracts; they performed their role as a reducing and capping agent and also exhibited a potent antibacterial activity against S. aureus (gram positive bacteria). Thus the biosynthesis of silver nanoparticles using edible mushroom extract will deserve to be a good candidate as an antibacterial agent.
Highlights
Despite the fact of advances in developing new drugs against various infectious diseases, till date there is a growing concern about the emergence and re-emergence of drug resistance
Silver nanoparticles have proved to be most effective as it has good antimicrobial efficacy against bacteria, viruses and other eukaryotic micro-organisms
The current study focused on some edible mushrooms which mediated the synthesis of silver nanoparticles and investigated for its antimicrobial activity
Summary
Despite the fact of advances in developing new drugs against various infectious diseases, till date there is a growing concern about the emergence and re-emergence of drug resistance. The use of nanoparticles is presently gaining impetus as they posses defined chemical, optical and mechanical properties They are most promising as they show good antibacterial properties due to their large surface area to volume ratio, which is coming up as the current interest in the researchers, due to the growing microbial resistance against metal ions, antibiotics and the development of resistant strains (Gong et al, 2007). The reduction of Ag+ ions by combinations of biomolecules found in these extracts, such as enzymes/proteins, amino acids, polysaccharides, and vitamins, is environmentally benign, yet chemically complex. This was achieved either through intracellular and extracellular synthesis (Acosta, 2009)
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