Abstract
Intracardiac Device and Prosthetic Infections: What Do We Know?
Highlights
Several prospective and retrospective studies have examined the rate of prosthetic valve endocarditis (PVE)
The risk decreased from 1.5% to 0.7% (P
Staphylococcus aureus and coagulasenegative are the predominant organisms in early PVE, regardless of a definition of less than two or less than 12 months [1,4,5,6,7,8]
Summary
Several prospective and retrospective studies have examined the rate of prosthetic valve endocarditis (PVE). The predominant organisms in late PVE are, not surprisingly, similar to those causing native valve endocarditis (NVE) with streptococci, enterococci and S aureus most commonly isolated [2,4,5,7,9]. There were fewer organisms per valve and a greater proportion of sterile valves in rabbits treated with vancomycin, gentamicin or rifampin as compared with a beta-lactam in these experiments, with no combinations tested [27].
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