Intra-Vitreal Injection of Triamcinolone Acetonide versus Bevacizumab for Management of Diabetic Macular Edema after Phaco Emulsification

Abstract

Background: Several studies were done to assess macular edema after phacoemulsification and after phacoemulsification with intravitreal injection of either triamcinolone acetonide or bevacizumab. Aim: to identify the effect of intravitreal injection of either Triamcinolone acetonide or Bevacizumab for the management of Diabetic macular edema after Phacoemulsification. Patients and Methods: Preoperative BCVA was recorded, Preoperative assessment with Fluorescein Angiography (FFA) and Optical Coherence Topography (OCT) was recorded. Patients were allocated into 3 groups, for all groups phacoemulsification and posterior chamber Intra ocular lens was done then in group A intravitreal injection of triamcinolone acetonide was done, group B intravitreal injection of bevacizumab was done, and group C only phacoemulsification and posterior chamber IOL was done. Postoperatively BCVA for each patient in each group and post operative FFA and assessment of the macular thickness with OCT were taken and recorded. Results:The study was carried on 39 patients, in group A there was an improvement of macular edema and reduction of central macular thickness postoperatively, also best corrected visual acuity was improved. In group B and group C there was deterioration of macular edema and increases in central macular thickness post operatively but best corrected visual acuity improved postoperatively. Conclusion: Intravitreal injection of triamcinolone acetonide is an effective method and more effective than bevacizumab for treatment of diabetic macular edema during phacoemulsification.