Abstract
Two cases of intra-uterine hyperparathyroidism secondary to maternal hypoparathyroidism are recorded. The skeletal manifestations of hyperparathyroidism were present at birth in one infant but not in the other. Both mothers had a remission of clinical tetany during their pregnancy. The infants' hyperparathyroidism may have been the result of hyperplasia of the fetal parathyroid glands in response to decreased placental transfer of calcium and fetal hypocalcemia. The relief of maternal tetany could have been accomplished either by passage of fetal parathyroid hormone or of calcium to the mother.
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