Abstract

Erythema Multiforme (EM) is an acute inflammatory disease of the skin and mucous membranes that causes a variety of skin lesions—hence the name “multiforme.” The oral lesions, typically inflammatory, are accompanied by rapidly rupturing vesicles and bullae. EM has several clinical presentations: from milder self-limiting form to severe life-threatening form that may present as either Stevens-Johnson syndrome or Toxic Epidermal Necrolysis (TEN).1 The most common triggers for episodes of EM are herpes simplex virus and drug reactions.2 EM includes both generalized symptoms such as fever and malaise and oral lesions starting as bullae on an erythematous base which break rapidly into irregular ulcers.1 Analysis of the dental literature indicated limited evidence about the use of dental removable prosthesis in oral lesions manifested by EM.3,4 This case report describes a multi-disciplinary approach for the treatment of erythema multiforme with the use of the intra-oral dental prosthetic device.

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