Abstract
BackgroundIntra-dialytic hypertension (IDH) is emerging as an important issue in hemodialysis patients. Its risk factors and clinical outcomes are unclear.MethodsA total of 73 prevalent hemodialysis patients were enrolled. They included 14 (19.2%) patients with baseline IDH and 59 patients without IDH. Their clinical parameters, laboratory parameters, and mortality were investigated over 78 months.ResultsThe risks factor of IDH included low serum potassium levels, low ultrafiltration, and low arm muscle area. Lower median survival was evident in the IDH group compared to the non-IDH group, but was not significantly different. After adjusting for relevant confounders for age, the IDH group displayed 2.846 times higher mortality rate than the non-IDH Group (adjusted hazard ratio: 2.846; 95% confidence interval: 1.081–7.490; P = 0.034).ConclusionIDH is associated with high mortality in hemodialysis patients. Clinicians should be aware of the risk factors. Future research studies are needed to explore the mechanisms involved in the association between IDH and mortality.
Highlights
The prevalence of hypertension in patients undergoing hemodialysis ranges from 65% to 85% [1]
Intra-dialytic hypertension (IDH) is associated with high mortality in hemodialysis patients
We aimed to identify factors related to the development of IDH and ascertain the relationship between IDH and mortality in hemodialysis patients
Summary
The prevalence of hypertension in patients undergoing hemodialysis ranges from 65% to 85% [1]. Hypertension results in cardiovascular complications in hemodialysis patients [2]. It is a powerful predictor of death [3]. Intra-dialytic hypertension (IDH), a unique form of hypertension observed in hemodialysis patients, has recently emerged as an important issue. Intra-dialytic hypertension (IDH) is emerging as an important issue in hemodialysis patients. Its risk factors and clinical outcomes are unclear
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