Abstract
Stroke is one of the main causes of death and disability worldwide, and the ischemic modality is responsible for the majority of these events. Despite its high occurrence and potentially unfavorable prognosis, the management options were scarce and barely effective until recent times, when a relatively new endovascular intervention with demonstrated superior efficacy as compared with that of classic management was reported in the medical literature. The theoretical basis of this study was conducted through research in virtual databases Public MEDLINE (PubMed) and Scientific Electronic Library Online (SciELO) using associations among the keywords “acute ischemic stroke”, “ischemic stroke”, “thrombectomy”, “endovascular,” and “intra-arterial thrombectomy”. Clinical trials, meta-analysis, and pertinent literature reviews published in the last two years were reviewed and 14 articles were selected for complete and critical evaluations. The results of the randomized clinical trials, consequences of implantation of the intra-arterial thrombectomy as routine management for eligible groups, cost-effectiveness, and the most related complications and outcomes associated with the procedure are critically explored throughout this study. Keywords: Stroke; ischemic stroke; thrombectomy; endovascular
Highlights
Stroke is one of the main causes of death and disability worldwide, and the ischemic modality is responsible for the majority of these events
Despite its high occurrence and potentially unfavorable prognosis, the management options were ineffective in many cases until recent times when a relatively new endovascular intervention associated with intravenous thrombolysis was reported to demonstrate superior efficacy as compared with that of the classic intravenous recombinant tissue plasminogen activator (IV tPA) management
We discuss the results of the randomized clinical trials published in the field, the logistic consequences of the intra-arterial thrombectomy implantation as a routine management tool for eligible groups, costeffectiveness, and the most related complications and outcomes associated with the procedure
Summary
Stroke is one of the main causes of death and disability worldwide, and the ischemic modality is responsible for the majority of these events. Despite its high occurrence and potentially unfavorable prognosis, the management options were scarce and barely effective until recent times, when a relatively new endovascular intervention with demonstrated superior efficacy as compared with that of classic management was reported in the medical literature. The results of the randomized clinical trials, consequences of implantation of the intra-arterial thrombectomy as routine management for eligible groups, cost-effectiveness, and the most related complications and outcomes associated with the procedure are critically explored throughout this study. We discuss the results of the randomized clinical trials published in the field, the logistic consequences of the intra-arterial thrombectomy implantation as a routine management tool for eligible groups, costeffectiveness, and the most related complications and outcomes associated with the procedure
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