Abstract
The effects of bilateral microinjections of a new potent and highly selective δ-opioid receptor agonist pCl-DPDPE (0.00,0.1,1.0, or 2.5 μg/side) were tested in rats for 60 min in activity monitors. The durations of horizontal movement time, rearing time, and stereotypy time were measured during six consecutive 10-min time blocks. The pCl-DPDPE resulted in short-lived biphasic effects of attenuation followed by potentiation for the three measures. These data in part replicate the behavioral effects of other δ-opioid receptor agonists.
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