Abstract
Sinonasal inverted papilloma is a rare benign tumor that accounts for 0.5-4% of all primitive nasosinus tumor. It has the potential to recur and exhibit malignant characteristics. Inverted papilloma recurring as adenocarcinoma is rare and even after exhaustive literature search only few cases could be found. The aim of the present study was to investigate the clinicopathological features and prognosis of intestinal type adenocarcinoma from inverted papilloma. We report a case of 54 old man who was operated two years ago from naso-sinusal inverted papilloma. He presented after one year nasal blockage and nasal bleeding. Clinical exam found a naso –sinusal tumor. He was operated and anatomopathological exam found an intestinal Adenocarcinoma type from inverted papilloma. A radiotherapy was indicated. The majority of inverted nasal papilloma are benign and treatment is complete local surgical removal. There is an associated real, but small risk of malignancy, which may coexist at the time of presentation or develop at a later time. Surgery plus postoperative radiotherapy was the predominant form of treatment.
Highlights
Sinonasal inverted papilloma (SNIP) is a rare benign tumor that accounts for 0.5-4% of all primitive nasosinus tumor [1, 2]
Malignant nasosinosal inverted papilloma is associated with squamous cell carcinoma, followed by malignant adenocarcinoma, while small cell carcinoma is rare
Long term follow up is recommended because inverted papillomas are known to have recurrence as malignancy and not every time the transformation is into squamous cell carcinoma, but rarely into adenocarcinomas
Summary
Sinonasal inverted papilloma (SNIP) is a rare benign tumor that accounts for 0.5-4% of all primitive nasosinus tumor [1, 2]. It has the potential to recur and exhibit malignant characteristics. Inverted papilloma (IP) recurring as adenocarcinoma is rare and even after exhaustive literature search only few cases could be found. The aim of the present study was to investigate the clinicopathological features and prognosis of intestinal type adenocarcinoma from IP. He was operated two years ago by paralateronasal technic for a right sinonasal inverted papilloma. He consulted for right nasal blockage and nasal bleeding. A preoperative sinus computed tomograhy showed a collapsed maxillary sinus filled with soft irregular tissue mass
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