Abstract

A 49-year-old heterosexual man presented to our outpatient clinic after a positive fecal occult blood test result. He had no remarkable past medical history and reported neither weight loss nor bowel symptoms. Colonoscopy showed a small erosive lesion in the cecum (Figure A), and biopsies were performed. Light microscopy revealed a band of spirochetes resembling a “false brush border” that was adherent to the border of the epithelial layer (Figure B, arrows; hematoxylin-eosin staining). This was highlighted by immunostaining for Treponema pallidum (Figure C, arrows).

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