Abstract
Background: Gastrectomy remains the only potentially curative treatment option for gastric cancer (GC). Although, it disrupts the gastric barrier. Subtotal gastrectomy with Billroth II reconstruction (SGB2) increase the gastric pH. Similar increase following proton-pump inhibitors (PPI) therapy has an impact on the gut microbiome composition, intestinal inflammation, and the host health. This study aimed to investigate if SGB2 is associated with PPI-like dysbiosis and if it is relevant for host health and long-term outcomes after surgery.
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Schedule a callMore From: Clinical oncology (Royal College of Radiologists (Great Britain))
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