Abstract
The bulk of folate activity in foodstuffs is in a poorly absorbed conjugated pteroyl-polyglutamate form, containing three to seven gamma-linked glutamate residues, and only a small portion is in an easily absorbable monoglutamate form. Deconjugation of the conjugated folate presumably occurs before the actual intestinal absorption of folate because the conjugated forms are not found in the plasma. The amount of deconjugating activity present in the fluids in the intestinal lumen (succus entericus) is inadequate to account for this deconjugation.1 Rosenberg, Streiff, Godwin and Castle, whose observations are reported in this issue, suggest that the mucosa of the duodenum and . . .
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