Abstract
Steve Oh is currently Principal Scientist and Director of the Bioprocess Internship Programme at the Bioprocessing Technology Institute, one of the biomedical research institutes under the Agency for Science Technology and Research. The focus of the Bioprocessing Technology Institute’s research is on developing simple yet rigorous and reproducible methods for producing high quality adherent stem cells (human pluripotent, multipotent stem cells and their differentiated derivatives, e.g., cardiomyocytes, neural cells and osteoblasts), for applications such as identifying drug candidates and tissue repair. Microcarriers have the versatility of different shapes, sizes, charges and the ability to present diverse extracellular matrices or peptides on their surfaces for cell expansion and differentiation. Microcarriers also enable adherent dependent stem cells to be cultured in suspension bioreactors instead of plasticware, which can readily be transferred to commercial manufacturing. They are also developing mo...
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