Abstract
Abstract Nosocomial infections due to methicillin-resistant Staphylococcus aureus (MRSA) strains are important because they have been associated with significantly higher morbidity, mortality, and hospital costs than have infections caused by methicillin-susceptible S. aureus (MSSA) strains. Thirty years ago, hospital infection control programs were created to control antibiotic-resistant infections, but MRSA infection rates in United States hospitals have continued increasing, leading many to wonder whether control is possible. Antibiotic restriction and cycling have had limited success controlling MRSA. Improving compliance with hand hygiene guidelines and effective hospital environmental disinfection would help but are unlikely to control the problem alone. The Centers for Disease Control and Prevention (CDC) has recommended contact precautions for patients known or suspected to be colonized or infected with MRSA. Many studies have shown that this approach works when enough active surveillance cultures are done to identify the reservoir for spread, but most health care facilities have not tried this approach.
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