Abstract

Interventions for basal cell carcinoma of the skin.

Highlights

  • Basal cell carcinoma (BCC) is the commonest cancer a ecting white-skinned individuals, and worldwide incidence is increasing

  • There may be little to no di erence regarding improvement of cosmetic outcomes between Mohs micrographic surgery (MMS) and surgical excision (SE), judged by participants and observers 18 months post-operatively; no raw data were available for this outcome

  • The overall quality of research on interventions for basal cell carcinoma (BCC) has improved since our 2007 review with the publication of several randomised controlled trials (RCTs) with long-term follow-up, but many of the included studies have provided low- or moderate-certainty evidence that should be interpreted with caution

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Summary

Introduction

Basal cell carcinoma (BCC) is the commonest cancer a ecting white-skinned individuals, and worldwide incidence is increasing. BCC is associated with significant morbidity and costs. New published studies and the development of non-surgical treatments meant an update of our Cochrane Review (first published in 2003, and previously updated in 2007) was timely. Basal cell carcinoma (BCC) is the most common skin cancer and the most common cancer found in white-skinned individuals (Dessinioti 2010; Lomas 2012; Madan 2016; Verkouteren 2017). Patients with BCC place a considerable burden on healthcare systems worldwide due to their high, increasing incidence and associated morbidity. The disability adjusted life years and healthcare costs of BCCs have risen significantly in recent decades (Verkouteren 2017)

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