Abstract
Thrombosis or embolism originating from large artery atherosclerosis causes 15% of the ischaemic strokes with transient or permanent functional deficit.1 In 2016, there were globally 9·6 million cases of ischaemic stroke, leading to 2·7 million deaths.2 The primary prevention of stroke is based on the control of lifestyle-related risk factors and the best medical therapy including optimal management of hypertension and diabetes, antithrombotic and lipid-lowering therapy, and smoking cessation.3 Patients with a significant atherosclerotic narrowing in their carotid artery can benefit from an additional surgical or endovascular intervention of the stenosis to reduce the risk of ischaemic stroke.
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