Abstract

Total biliary diversion markedly depressed urinary excretion of I/sup 131/ intravenously administered. The effect was apparent within 2 hr post choledochostomy. Fasting reduced urinary excretion of I/sup 131/ to a minor extent; operative trauma had no effect. Treatment of bile fistula rats with donor bile and/or iodinated drinking water significantly increased I/sup 131/ excretion. I/sup 131/ content of bile was signifi cantly reduced in bile fistula rats only through combined treatment with donor rat bile and iodinated drinking water. I/sup 131/ content in urine paralleled that of sodium under some conditions but not in others. (auth)

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