Interrelationships of methionine and vitamin B6 in human subjects.

Abstract

Summary1. A study of the interrelationship of methionine and pyridoxine was made in adult human subjects maintained on a semi-synthetic diet low in vit. B6. 2. No effect of a high dosage of methionine on the urinary excretion of B6 and its metabolites was observed in the study. 3. The role of vit. B6 in the methylation of nicotinamide is shown by the increased urinary excretion of N1-methylnicotinamide by human subjects, when given methionine plus pyridoxine but not when given only methionine.