Interrelation of bone mineral density with kneeosteoarthrosis

Abstract

Association of bone mineral density (BMD) of axial skeleton with age of the disease onset as well as with clinical traits and instrumental investigation findings has been studied in osteoarthritic patients. 116 females with primary knee OA, 74 ofwhich exhibited normal or increased BMD at lumbar spine and 42, with osteoporosis were included in the study. Knee joint pain was measured using visual analog scale (VAS). All the patients were subjected to X-ray analysis of their knee joints at two sites (OA stage was determined according to Kellgren-Lawrence scale), densitometry at lumbar spine and proximal femur using QDR-4500W (Hologic), MRT, and ultrasonography of the knee joints. We determined that the increasedBMD at lumbar spine was associated with early OA onset, more pronounced X-ray changes in the knee joints and higher frequency of varus deformation development in tibial bones.