Abstract
Liquid-based perinatal life support (PLS) technology will probably be applied in a first-in-human study within the next decade. Research and development of PLS technology should not only address technical issues, but also consider socio-ethical and legal aspects, its application area, and the corresponding design implications. This paper represents the consensus opinion of a group of healthcare professionals, designers, ethicists, researchers and patient representatives, who have expertise in tertiary obstetric and neonatal care, bio-ethics, experimental perinatal animal models for physiologic research, biomedical modeling, monitoring, and design. The aim of this paper is to provide a framework for research and development of PLS technology. These requirements are considering the possible respective user perspectives, with the aim to co-create a PLS system that facilitates physiological growth and development for extremely preterm born infants.
Highlights
Preterm birth is the leading cause of perinatal and neonatal mortality and life-long morbidity world-wide [1]
We present the consensus opinion of this consortium, and propose our vision on the design requirements of PLS-based development
PLS could be an answer to the dilemma of the benefits outweighing the risks of continuing pregnancy vs. the health risks involved for either the mother or the infant [17]
Summary
Preterm birth is the leading cause of perinatal and neonatal mortality and life-long morbidity world-wide [1]. Especially extremely preterm born infants (
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