Abstract

Liquid-based perinatal life support (PLS) technology will probably be applied in a first-in-human study within the next decade. Research and development of PLS technology should not only address technical issues, but also consider socio-ethical and legal aspects, its application area, and the corresponding design implications. This paper represents the consensus opinion of a group of healthcare professionals, designers, ethicists, researchers and patient representatives, who have expertise in tertiary obstetric and neonatal care, bio-ethics, experimental perinatal animal models for physiologic research, biomedical modeling, monitoring, and design. The aim of this paper is to provide a framework for research and development of PLS technology. These requirements are considering the possible respective user perspectives, with the aim to co-create a PLS system that facilitates physiological growth and development for extremely preterm born infants.

Highlights

  • Preterm birth is the leading cause of perinatal and neonatal mortality and life-long morbidity world-wide [1]

  • We present the consensus opinion of this consortium, and propose our vision on the design requirements of PLS-based development

  • PLS could be an answer to the dilemma of the benefits outweighing the risks of continuing pregnancy vs. the health risks involved for either the mother or the infant [17]

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Summary

Introduction

Preterm birth is the leading cause of perinatal and neonatal mortality and life-long morbidity world-wide [1]. Especially extremely preterm born infants (

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