Abstract
1 Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland 2 Department of Diagnostics, Faculty of Medicine, University of Oulu, Oulu, Finland 3 Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland 4 Division of Brain Sciences, Academic Department of Neuro-otology, Imperial College London, Charing Cross Hospital Campus, London, UK *Correspondence: ed.roberts@imperial.ac.uk
Highlights
SECTION In this issue Mandl and colleagues replicated the findings of a previous study (Mandl et al, 2008) in which they explored task-related changes in fractional anisotropy (FA) along white matter (WM) tracts using functional diffusion tensor imaging
WM blood oxygenation level dependent (BOLD) activation is a very rarely reported phenomenon. It follows that the relative gray matter (GM)/WM BOLD signal ratio is very likely to increase during a stimulus-induced positive BOLD period, and decrease during the post-stimulation negative BOLD period
Changes in the GM BOLD signal would appear to be the most likely explanation, it is still unclear to what extent and precisely how this could impact on FA measurements in central white matter pathways
Summary
SECTION In this issue Mandl and colleagues replicated the findings of a previous study (Mandl et al, 2008) in which they explored task-related changes in fractional anisotropy (FA) along white matter (WM) tracts using functional diffusion tensor imaging (fDTI). They report increased FA in WM of thalamocortical pathways during tactile stimulation and in the optic radiations during visual stimulation, while only minor changes in mean diffusivity (MD) and blood oxygenation level dependent (BOLD) contrast were observed.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
