Abstract

IntroductionLung cancer has a poor prognosis that varies internationally when assessed by the two major histological subgroups (non-small cell (NSCLC) and small cell (SCLC)).Method236 114 NSCLC and 43 167 SCLC...

Highlights

  • Lung cancer has a poor prognosis that varies internationally when assessed by the two major histological subgroups [non-small cell (NSCLC) and small cell (SCLC)]

  • Lung cancer is the leading cause of cancer death among men and women worldwide, with an estimated 1.6 million deaths, or nearly 20% of all cancer deaths, occurring in 2018.1 Lung cancer is categorised into two main histological groups - small cell lung carcinoma (SCLC) and non-small cell lung carcinoma (NSCLC) - with SCLC patients generally having poorer outcomes compared to NSCLC.[2]

  • The International Cancer Benchmarking Partnership (ICBP), a consortium of clinicians, policy-makers, researchers, and cancer data experts, has previously described lung cancer survival differences across high-income countries[7] and concluded that stage at diagnosis and histological type explained some of the international variation in lung cancer survival in 2004-2007.2 In this study, we extend this prior work by assessing the most up-to-date lung cancer survival statistics by sex and stage at diagnosis for NSCLC and SCLC, using population-based data from seven countries

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Summary

INTRODUCTION

Lung cancer is the leading cause of cancer death among men and women worldwide, with an estimated 1.6 million deaths, or nearly 20% of all cancer deaths, occurring in 2018.1 Lung cancer is categorised into two main histological groups - small cell lung carcinoma (SCLC) and non-small cell lung carcinoma (NSCLC) - with SCLC patients generally having poorer outcomes compared to NSCLC.[2] Marked sex differences in survival have been previously reported, with females having a more favourable prognosis.[3,4,5,6]. The International Cancer Benchmarking Partnership (ICBP), a consortium of clinicians, policy-makers, researchers, and cancer data experts, has previously described lung cancer survival differences across high-income countries[7] and concluded that stage at diagnosis and histological type explained some of the international variation in lung cancer survival in 2004-2007.2 In this study, we extend this prior work by assessing the most up-to-date lung cancer survival statistics by sex and stage at diagnosis for NSCLC and SCLC, using population-based data from seven countries

METHODS
All patients
Findings
DISCUSSION
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