Year-end Sale % OFF 
Abstract
In this study, internal size variations in the VanA gene cluster Tn 1546, encoding resistance to glycopeptides, is described. Studies of previously uncharacterized size variations of an internal region, encoding the vanX and vanY genes of Tn 1546, revealed that these variations were due to the presence of the IS sequence, IS 1216V. This IS sequence has previously been found integrated in Tn 1546. Integration of the IS 1216V element created both deletions and a duplication in a non-essential region of Tn 1546. In several isolates, the entire vanY gene was deleted, proving that this gene is non-essential for vancomycin resistance.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
